1. Christian G.D.: Analytical Chemistry. John Wiley & Sons, Inc. New York – Chichester – Brisbane – Toronto – Singapore 2004.

2. Harvey D.: Modern Analytical Chemistry. McGraw Hill, Boston, 2000.

3. Harvey D.: Analytical Chemistry 2.1. LibreText. 2021.

4. Labuda J. a kol.: Analytická chémia. Vydavateľstvo STU. Bratislava 2019.

5. R. G. Brereton: Chemometrics., Wiley, Chichester, 2003.

6. M. Meloun, J. Militký: Kompendium statistického zpracování dat., Academia, Praha 2006.

Slovak

The course is implemented by full-time or distance method (MS Team, Google Meet, BBB) or a combined method.

Sampling and processing in analytical chemistry, basic rules of sampling. Representative sample, homogeneous sample. Sample pretreatment, selection of analytical method.

Types of chemical equilibria in solutions. Protolytic equilibria. Oxidation-reduction equilibria. Precipitation equilibria. Complex-forming equilibria. Use of analytical reaction in quantitative analysis. Methods of suppressing adverse reactions. Masking in analytical chemistry.

Basic principles and classification of separation methods. Extraction, principle, classification of extraction methods and their use in sample preparation - LLE, SPE, SPME, etc. Basic principles of chromatography, general description of chromatographic process. Qualitative and quantitative analysis in chromatography. Principles of chromatographic separation in gas chromatography (GC). Theoretical bases of liquid chromatography (LC). Gel permeation chromatography (GPC), ion exchange chromatography (IEC), supercritical fluid chromatography (SCF), principles and applications. UPLC versus HPLC. Electromigration methods, principle, classification and their use.

Principles of the most important instrumental analytical methods. Electrochemical analytical methods, typical applications. Voltammetric methods, potentiometric methods, coulometry. Electrochemical dissolution analysis. Electrochemical detectors in flow systems.

Spectral analytical methods. Atomic and molecular spectroscopy: Principles, division. Atomic spectra, origin, analytical use. Basic differences in emission and absorption methods. Excitation sources. Radiation decomposition. Radiation detection. Matrix effects and their elimination. Implementation of analytical calibration. Atomic absorption spectrometry. Molecular spectrophotometry - UV/VIS, IR, MS. Thermal analysis.

Fundamentals of mathematical and statistical methods used in analytical chemistry. Probability distribution of measurement results, classical and robust estimates of mean and variance. Statistical tests and their application. Accuracy, precision, and reliability of results. Calibration in analytical chemistry, linear and nonlinear models.