Email:
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ivan.kovac@upjs.sk | |
Homepage:
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https://www.upjs.sk/LF/zamestnanec/ivan.kovac | |
Faculty:
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LF UPJŠ
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Pavol Jozef Šafárik University in Košice Faculty of Medicine
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Department:
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2. ChK
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2nd Department of Surgery
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Office:
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HK0O116 | |
Phone:
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ORCID ID:
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0000-0001-6717-5858 |
Profile courses
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Surgery - general medicine, 1 a 2 degree
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surgery - dental medicine, 1 a 2 degree
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surgery - general medicine, 1st and 2nd degree
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surgery - dental medicine, 1st and 2nd degree
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Selected publications
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ADC7 Plantago lanceolata L. water extract induces transition of fibroblasts into myofibroblasts and increases tensile strength of healing skin wounds / Ivan Kováč ... [et al.]. In: Journal of Pharmacy and Pharmacology. - ISSN 0022-3573. - Vol. 67, no. 1 (2015), s. 117-125. 2015 CC [KOVÁČ, Ivan (20%) - ĎURKÁČ, Ján (2%) - HOLLÝ, Martin (2%) - JAKUBČOVÁ, Katarína (2%) - GÁLOVÁ-PERŽEĽOVÁ, Vlasta (2%) - MUČAJI, Pavel (2%) - ŠVAJDLENKA, Emil (2%) - SABOL, František (2%) - LEGÁTH, Jaroslav (2%) - BELÁK, Jozef (2%) - SMETANA, Karel, jr. (2%) - GÁL, Peter (60%) ] Ohlasy: ( 13 ) [1] ALAMGEER, S.A. et al. Indigenous medicinal plants of Pakistan used to treat skin diseases: a review. In Chinese Medicine, 2018, vol. 13, art. no. 52 [1] BAHADORI, M.B. et al. Plantago lanceolata as a source of health-beneficial phytochemicals: Phenolics profile and antioxidant capacity. In Food Bioscience, 2020, vol. 34, art. no. 100536. [1] CONNELLY, E., GENIO Del, C.I., HARRISON, F. Data mining a medieval medical text reveals patterns in ingredient choice that reflect biological activity against infectious agents. In mBio, 2020, roč. 11, č. 1, art. no. e03136-19. [1] EL-FERJANI, R.M. et al. In vivo Assessment of Antioxidant and Wound Healing Improvement of a New Schiff Base Derived Co (II) Complex in Rats. In Scientific Reports, 2016, vol. 6, art. no. 38748. [1] GENC, Y. et al. The inhibitory effects of isolated constituents from Plantago major subsp. major L. on collagenase, elastase and hyaluronidase enzymes: Potential wound healer. In Saudi Pharmaceutical Journal, 2020, vol. 28, no. 1, s. 101-106. [1] GONÇALVES, S., ROMANO, A. The medicinal potential of plants from the genus Plantago (Plantaginaceae). In Industrial Crops and Products, 2016, vol. 83, s. 213-226. [1] HANCIOĞLU, S. et al. Histopathological and mechanical effects of ankaferd blood stopper® on wound healing in rats: An experimental model. In Turkish Journal of Medical Sciences, 2020, roč. 50, č. 5, s. 1428-1433. [1] KALANTARI, A. et al. Self-nanoemulsifying drug delivery systems containing plantago lanceolata—an assessment of their antioxidant and antiinflammatory effects. In Molecules, 2017, vol 22, no. 10, art. no. 1773 [1] KURT, B. et al. Effects of Plantago lanceolata L. extract on full-thickness excisional wound healing in a mouse model. In Biotechnic and Histochemistry, 2018, vol. 93, no. 4, s. 249-257. [1] LAMMEL, C. et al. Peucedanum ostruthium inhibits e-selectin and VCAM-1 expression in endothelial cells through interference with nf-κb signaling. In Biomolecules, 2020, roč. 10, č. 9, art. no. 1215, s. 1-22. [1] POLJŠAK, N., KREFT, S., KOČEVAR GLAVAČ, N. Vegetable butters and oils in skin wound healing: Scientific evidence for new opportunities in dermatology. In Phytotherapy Research, 2020, vol. 34, no. 2, s. 254-269. [3] AL-HUSSAINY, A.D.I., IDBAEES, H.I., RHUDA, S.A.A. Advanced Search Fulltext Antibacterial effect of phenolic extracts of Plantago lanceolata, Convolvulus arvensis and Euphorbia granulate leaves against human pathogenic bacteria. In Journal Of Wassit For Science & Medicine, 2016, vol. 9, no 1, s. 16-29 [3] GUIMARÃES, A.L.S. et al. Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus Aureus: Importance in Compounding for Wound Care. In International Journal of Pharmaceutical Compounding, 2016, vol. 20, no. 1, s. 58-62 MSEP 025539
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Should open excisions and sutured incisions be treated differently? A review and meta-analysis of animal wound models following low-level laser therapy / Peter Gál ... [et al.]. In: Lasers in Medical Science=LIMS. - ISSN 0268-8921. - Roč. 33, č. 6 (2018), s. 1351-1362. - DOI 10.1007/s10103-018-2496-7 [GÁL, Peter (35%) - STAUSHOLM, Martin Bjorn (35%) - KOVÁČ, Ivan (15%) - DOSEDLA, Erik (2%) - LUCZY, Ján (3%) - SABOL, František (5%) - BJORDAL, Jan Magnus (5%) ] Ohlasy: ( 1 ) [1] REYNOLDS, M. A. - AICHELMANN-REIDY, M. E. - ROSEN, P. S.. Lasers in periodontal and peri-implant therapy: Challenges and opportunities. In Emerging Therapies in Periodontics. 2020. ISBN 9783030429904, s. 231-258. MSEP 030400
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ADC11 Aesculus hippocastanum L. extract does not induce fibroblast to myofibroblast conversion but increases extracellular matrix production in vitro leading to increased wound tensile strength in rats [elektronický zdroj] / Ivan Kováč ... [et al.]. - Projekt: Vývoj aktívnych krytí rán na báze hydrogélov obsahujúcich rastlinné extrakty stimulujúce hojenie rán u zdravých a diabetických potkanov - VEGA 1/0319/20 ; Modulácia hojenia rán rastlinnými extraktmi u zdravých a diabetických potkanov so zameraním na repík lekársky - VEGA 1/0561/18 ; Bunkové interakcie v nádorovom mikroprostredí a ich farmakologické ovplyvnenie - APVV APVV-16-0446 ; Komplexní poranění a funkční poruchy páteře, pánve, končetin a syntopicky blízkých orgánů a struktur - PROGRES Q37 ; BIOCEV – Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University project (CZ.1.05/1.1.00/02.0109), ; Komplexní onkologický program II - Program Progres Q28 ; Medicínsky univerzitný vedecký park v Košiciach (MediPark, Košice - Fáza II.) - ITMS2014+ 313011D103. In: Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry. - ISSN 1420-3049. - Roč. 25, č. 8 (2020), art. no. 1917, s. [1-14], online. - Spôsob prístupu: https://www.scopus.com/record/display.uri?eid=2-s2.0-85083767654&origin=resultslist. - DOI 10.3390/molecules25081917 [KOVÁČ, Ivan (10%) - MELEGOVÁ, Nikola (5%) - ČOMA, Matúš (5%) - TAKÁČ, Peter (5%) - KOVÁČOVÁ, Katarína (5%) - HOLLÝ, Martin (5%) - ĎURKÁČ, Ján (5%) - URBAN, Lukáš (5%) - KAŇUCHOVÁ, Miriam (5%) - ŠVAJDLENKA, Emil (5%) - MOJŽIŠOVÁ, Gabriela (5%) - ZAJÍČEK, Róbert (5%) - SZABÓ, Pavol (5%) - MUČAJI, Pavel (5%) - GÁL, Peter (25%) ] MSEP 032968
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Agrimonia eupatoria L. and Cynara cardunculus L. Water infusions: phenolic profile and comparison of antioxidant activities / Anika Kuczmannová ... [et al.]. - Projekt: VEGA 1/0299/13 ; VEGA 1/0646/14 ; Iné granty domáce FaF UK/15/2015. In: Molecules. - ISSN 1420-3049. - Vol. 20 (2015), s. 20538 - 20550. 2015 WoS [KUCZMANNOVÁ, Anika (20%) - GÁL, Peter (20%) - VARINSKÁ, Lenka (14%) - TREML, Jakub (1%) - KOVÁČ, Ivan (10%) - NOVOTNÝ, Martin (10%) - VASILENKO, Tomáš (10%) - DALL´ACQUA, Stefano (1%) - NAGY, Milan (4%) - MUČAJI, Pavel (10%) ]
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ADC8 Pharmacological activation of estrogen receptor-alfa and -beta differentially modulates keratinocytes differentiation with functional impact on wound healing / Vlasta Peržeľová ... [et al.]. - Projekt: VEGA VEGA 1/0299/13 ; VEGA VEGA 1/0404/15 ; VEGA VEGA 1/0048/15 ; MŠ SR - APVV APVV-0408-12 ; MŠ SR - APVV APVV-14-0731 ; Iné granty zahraničné Univerzita Karlova v Praze UNCE 204013 ; Iné granty zahraničné Univerzita Karlova v Praze PRVOUK 27 ; Iné granty zahraničné European Regional Development Fund BIOCEV CZ.1.05/1.1.00/02.0109 ; Iné granty zahraničné European Commission GlycoHIT 260600 ; Iné granty zahraničné European Commission Marie Curie ITN network GLYCOPHARM 317297. In: International Journal of Molecular Medicine. - ISBN 1107-3756. - Vol. 37, no. 1 (2016), s. 21-28. 2016 CC [GÁLOVÁ-PERŽEĽOVÁ, Vlasta (10%) - SABOL, František (10%) - VASILENKO, Tomáš (5%) - NOVOTNÝ, Martin (5%) - KOVÁČ, Ivan (6%) - SLEZÁK, Martin (1%) - ĎURKÁČ, Ján (1%) - HOLLÝ, Martin (1%) - PILÁTOVÁ, M. (7%) - SZABÓ, Pavol (1%) - VARINSKÁ, Lenka (10%) - ČRIEPOKOVÁ, Zuzana (1%) - KUČERA, Tomáš (1%) - KALTNER, Herbert (1%) - ANDRÉ, Sabine (1%) - GABIUS, Hans-Joachim (1%) - MUČAJI, Pavel (1%) - SMETANA, Karel, jr. (1%) - GÁL, Peter (36%) ] Ohlasy: ( 8 ) [1] BAIDA, G. et al. Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin. In Oncotarget, 2020, vol. 11, no. 4, s. 409-418. [1] CHENG, X. et al. Roles of ERα during mouse trophectoderm lineage differentiation: Revealed by antagonist and agonist of ERα. In Development Growth and Differentiation, 2016, Vol. 58, no. 3, s. 327-338 [1] DAMROSE, E.J. et al. Increased Expression of Estrogen Receptor Beta in Idiopathic Progressive Subglottic Stenosis. In Laryngoscope, 2020, roč. 130, č. 9, s. 2186-2191. [1] HORIKOSHI, Y. et al. α-Tocopherol promotes HaCaT keratinocyte wound repair through the regulation of polarity proteins leading to the polarized cell migration. In BioFactors, 2018, vol. 44, no. 2, s. 180-191. [1] HORNG, H.-C. et al. Estrogen effects on wound healing. In International Journal of Molecular Sciences, 2017, vol. 18, no. 11, art. no. 2325. [1] LOPES-MENEZES, V.C. et al. Acute body sodium depletion induces skin sodium mobilization in female Wistar rats. In Experimental Physiology, 2019, vol. 104, no. 12, s. 1754-1761. [1] SHENG, P. et al. Overexpression of androgen, oestrogen and progesterone receptors in skin lesions of Becker’s Naevus. In Acta Dermato-Venereologica, 2018, vol. 98, no. 9, s. 867-872. [1] VIANO, M. et al. A thermal gradient modulates the oxidative metabolism and growth of human keratinocytes. In FEBS Open Bio, 2017, vol. 7, no. 12, s. 1843-1853. MSEP 026983
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Selected projects
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VEGA -1/0048/15: Vplyv estrogénovej substitačnej terapie na hojenie rán a prežívanie kožných lalokov. Spoluriešitelia projektu: Doc. MUDr. Jozef Belák, PhD., MUDr. Marián Kudláč, MUDr. Róbert Šimon, PhD., MUDr. Ivan Kováč Obdobie riešenia: od roku 1.2015 do roku 12.2017 |
Awards
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2010 - UPJŠ Rector's award for scientific research activities 2011 - UPJŠ Rector's Award for scientific research
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Projects
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Ischemic model of gastric graft survival in the construction of exophageal-gastro anastomosis / VVGS2020-1648 /
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