RNDr. Ivana Špaková, PhD.

	Email:	ivana.spakova@upjs.sk
	Homepage:	https://www.upjs.sk/LF/zamestnanec/ivana.spakova
	Faculty:	LF UPJŠ - Pavol Jozef Šafárik University in Košice Faculty of Medicine
	Department:	ULCHBKB - Department of Medical and Clinical Biochemistry
	Office:
	Phone:	+421 55 234 3259
	ORCID ID:	0000-0003-3664-9111

RNDr. Ivana Spakova, PhD. has been working as an assistant professor at the Department of Medical and Clinical Biochemistry, Faculty of Medicine, UPJŠ in Košice since 2020, in the previous years 2017-2020 as a researcher. After completing her university studies in the Biochemistry study program in 2013, she began her doctoral studies in Clinical Biochemistry at the UPJŠ Faculty of Medicine, where she completed a study stay in a working group focused on molecular biochemistry in 2016 (Prof. Dr. Ondrej Slabý, PhD.) at CEITEC in the Czech Republic and in 2017 a study visit to a working group focused on live imaging (Prof. Dr. Wolfgang Graier, PhD.) at the Medical University of Graz in Austria. After successfully defending her dissertation, she obtained a PhD. in 2017. As part of his research activities, he studies short non-coding nucleic acids and their role in the regulation of gene expression, mitochondrial metabolism and the genome. Since 2013, she has been a co-investigator of VEGA and APVV projects and co-author of 12 original scientific papers published in CC journals (Scopus, HI = 4).

Higher education and further qualification growth

First degree of higher education:

Pavol Jozef Šafárik University in Košice, 2008-2011, Chemistry

Second degree of higher education:

Pavol Jozef Šafárik University in Košice, 2011-2013, Biochemistry

Third degree of higher education:

Pavol Jozef Šafárik University in Košice, 2013-2017, Clinical Biochemistry

Research /art/ teacher profile

Display details

Profile courses
Medical Biochemistry 2, I.+II. degree
Medical Biochemistry 1,2, I.+II. degree
Medical Biochemistry 1,2, I.+II. degree
Medical Chemistry, I.+II. degree
Laboratory Diagnostics in Clinical Practice, I.+II. degree
Selected publications
ADC - Špaková Ivana, Zelko Aurel, Rabajdová Miroslava, Kolaršik Peter, Rosenberger Jaroslav, Zavacká Martina, Mareková Mária, Madarasová Gecková Andrea, Dijk Jitse Pieter, Reijneveld Sijmen A. - MicroRNA molecules as predictive biomarkers of adaptive responses to strength training and physical inactivity in haemodialysis patients - Scientific Reports - 2020 - 10, 15597, IF 3.998, Q1, citation: 4-times
ADC - Rabajdová Miroslava, Urban Peter, Špaková Ivana, Saksun Ladislav, Dudič Rastislav, Ostró Alexander V., Caprnda Martin, Kružliak Peter, Adamek Mariusz, Mareková Mária - The crucial role of emilin 1 gene expression during progression of tumor growth - Journal of Cancer Research and Clinical Oncology - 2016 - 11, 4-32, IF 3.503 (2016), Q1, citationé: 8-times
ADC - Smolko Lukáš, Špaková Ivana,Klepcová Zuzana, Dubazová katarína, Samoľová E., Rabajdová Miroslava, Mareková Mária - Zinc(II) niflumato complex with neocuproine: Synthesis, crystal structure, characterization and cytotoxic effects on human endometrial cell lines - Journal of Molecular Structure - 2021 - 1237, 130312, IF 2.618, Q2, citation: 1-times
ADC - Špaková Ivana, Graier Wolfgang, Rabajdová Miroslava, Dubayová Katarína, Nagyová Vladimíra, Mareková Mária - Hypoxia factors supression effect on the energy metabolism of a malignant melanoma cell SK-MEL-30 - European Review for Medical and Pharmacological Sciences - 2020 - 24, 4909-4920, IF 2.912, Q2, citation: 4-times
ADC - Rabajdová Miroslava, Špaková Ivana, Klepcová Zuzana, Smolko Lukáš, Abrahamovská Micheala, Urdzík Peter, Mareková Mária - Zinc(II) niflumato complex effects on MMP activity and gene expression in human endometrial cell lines - Scientific Reports - 2021 - 11, 19086, IF 4.379, Q1, citation: 0-times
Selected projects
VEGA 1/0333/20: Tear fluid and saliva in preventive, predictive and personalized medicine - responsible researcher: doc. RNDr. Vladimíra Tomečková, PhD.
VEGA 1/0596/19: Identification and validation of new biomarkers of prodromal Parkinson's disease in a large cohort of patients with sidiopathic REM sleep behavior - responsible researcher: doc. MUDr. Matej Škorvánek, PhD.
APVV-18-0547: New biomarkers of prodromal Parkinson's disease - responsible researcher: doc. MUDr. Matej Škorvánek, PhD.
VEGA 1/0372/17: Use of miRNA and fluorescence techniques in the diagnosis of bladder tumors - responsible researcher: prof. Ing. Mária Mareková, CSc.
VEGA 1/0873/16: Characterization of endometrial carcinoma microenvironment - responsible researcher: doc. RNDr. Miroslava Rabajdová, PhD.
International mobilities and visits
Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Institute of Molecular Biology and Biochemistry, Medical univerzity of Graz, Auenbruggerplatz 2, 8036 Graz, Austria, August 2021 - September 2021, Erasmus+
Central European Institute of Technology, Masaryk University in Brno, Kamenice 753/5, 62500 Brno, Czech Republic, 2019 (several times for one week stay), Erasmus+
Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Institute of Molecular Biology and Biochemistry, Medical univerzity of Graz, Auenbruggerplatz 2, 8036 Graz, Austria, Február 2017 - Júl 2017, Ernst Mach Scholarship
Central European Institute of Technology, Masaryk University in Brno, Kamenice 753/5, 62500 Brno, Czech Republic, February 2016 - April 2016, Erasmus+

Additional information

Awards

EFLM Young Scientist 2017

Projects

Open: - co-worker: VEGA1/0873/16, VEGA1/0620/19, VEGA1/0596/19 Closed: https://www.upjs.sk/public/media/9690/Projects_2017.pdf

International collaboration

CEITEC Brno (Czech Republic); Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Institute of Molecular Biology and Biochemistry Medical University of Graz (Austria)

Interesting links

publications: https://www.upjs.sk/public/media/9691/Publications-16.pdf

Further information

Taught courses and supervised study programmes