 |
Email:
|
jan.mojzis@upjs.sk |
|
Homepage:
|
https://www.upjs.sk/LF/zamestnanec/jan.mojzis | |
|
Faculty:
|
LF UPJŠ
-
Pavol Jozef Šafárik University in Košice Faculty of Medicine
|
|
|
Department:
|
UFR
-
Department of Pharmacology
|
|
|
Office:
|
MA4O17 | |
|
Phone:
|
+421 55 234 3485 | |
|
ORCID ID:
|
0000-0002-7974-4525 |
|
Overview of the responsibility for
the delivery, development and quality assurance of the study programme or its part
at the university in the current academic year
|
|
Study programme: Medical Pharmacology - member of jury for defendence of PhD; co-guarant of doctoral study program medical pharmacology, study field: Pharmacy, III. degree
|
|
Profile courses
|
|
Pharmacology 2 - General Medicine, I.+II. degree
|
|
Pharmacology 2 - Dentistry, Dental Medicine, I.+II. degree
|
|
Pharmacology - Medical Pharmacology, III. degree
|
|
Overview of the responsibility for
the development and quality of the field of habilitation procedure and inaugural procedure
in the current academic year
|
|
Name of the field of habilitation procedure and inaugural procedure:
Medical Pharmacology; co-guarant, study field to which it is assigned: Pharmacy
|
|
Selected publications
|
|
ADC: Mirossay L, Varinská L, Mojžiš J. Antiangiogenic Effect of Flavonoids and Chalcones: An Update. Int J Mol Sci. 19, pii: E27., 2018 (IF=3,226; Q1) cit. 48 x |
|
ADC: Kapinova, A., Stefanicka, P., Kubatka, P., Zubor, P., Uramova, S., Kello, M., Mojzis, J., Blahutova, D., Qaradakhi, T., Zulli, A., Caprnda, M., Danko, J., Lasabova, Z., Busselberg, D., Kruzliak, P.: Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research. Biomed Pharmacother. 96, 1465–1477, 2017 (IF= 2,326; Q1) cit. 51 x |
|
ADM: Kello M, Takac P, Kubatka P, Kuruc T, Petrova K, Mojzis J. Oxidative Stress-Induced DNA Damage and Apoptosis in Clove Buds-Treated MCF-7 Cells. Biomolecules 10, pii: E139, 2020 (IF=4,649; Q1) cit. 8 x |
|
ADM: Takac P, Kello M, Vilkova M, Vaskova J, Michalkova R, Mojzisova G, Mojzis J. Antiproliferative Effect of Acridine Chalcone Is Mediated by Induction of Oxidative Stress. Biomolecules 10, pii: E345, 2020 (IF=4,649; Q1) cit. 12 x |
|
ADM: Michalkova, R.; Mirossay, L.; Gazdova, M.; Kello, M.; Mojzis, J. Molecular Mechanisms of Antiproliferative Effects of Natural Chalcones. Cancers 13, 2730 2021 (IF=6,639; Q1) cit: 8x |
|
ADC: Kubatka P, Kello M, Kajo K, Samec M, Liskova A, Jasek K, Koklesova L, Kuruc T, Adamkov M, Smejkal K, Svajdlenka E, Solar P, Pec M, Büsselberg D, Sadlonova V, Mojzis J. Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma. Int J Mol Sci. 22, 183, 2021 (IF= 5,923; Q1); cit 11x |
|
ADM: Kello M, Kuruc T, Petrova K, Goga M, Michalova Z, Coma M, Rucova D, Mojzis J. Pro-Apoptotic Potential of Pseudevernia furfuracea (L.) Zopf Extract and Isolated Physodic Acid in Acute Lymphoblastic Leukemia Model In Vitro. Pharmaceutics. 13, 2173, 2021. (IF=6,321; Q1) |
|
ADC: Samec M., Liskova A., Koklesova L., Samue SM., Zha K., Buhrmann C., Varghese E., Abotaleb M., Qaradakhi T., Zulli A., Kello M., Mojzis J., Zubor P., Kwon TK., Shakibaei M., Büsselberg D., Sarria GR., Golubnitschaja O., Kubatka P.: Flavonoids against the Warburg phenotype—concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism. EPMA Journal 11, 377-398, 2020 (IF=6,543; Q1), cit 21 x |
|
ADC: Takac P., Kello M., Bago Pilatova M., Kudlickova Z., Vilkova M., Slepcikova P., Petik P., Mojzis J.: New chalcone derivative exhibits antiproliferative potential by inducing G2/M cell cycle arrest, mitochondrial-mediated apoptosis and modulation of MAPK signalling pathway. Chem Biol Interac 292, 37–49, 2018. (IF=3,296; Q1); cit. 22x |
|
ADC: Kubatka P, Kello M, Kajo K, Kruzliak P, Výbohová D, Mojžiš J, Adamkov M, Fialová S, Veizerová L, Zulli A, Péč M, Statelová D, Grančai D, Büsselberg D. Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model. Eur J Nutr. 56, 1303-1316, 2017 (IF=3,467; Q1). cit. 21x |
|
Selected projects
|
|
APVV–0408–12: Galectins and angiogenesis . 2013-2017: PI: prof. MVDr. Ján Mojžiš, DrSc. |
|
APVV-16-0446; Cell interactions in the tumor microenvironment and their pharmacological modulations. 2017-2021; PI from 2018 - prof. MVDr. Ján Mojžiš, DrSc. |
|
VEGA 1/0322/14: Indole phytoalexins - mechanism of their anti-proliferative effect. 2014-2016. PI: prof. MVDr. Ján Mojžiš, DrSc. |
|
VEGA 1/0753/17; Effect of natural compunds on tumor microenvironment. 2017-2020, PI: prof. MVDr. J. Mojžiš, DrSc. |
|
VEGA 1/0539/21; Fibroblasts and tumor microenvironment: cell interactions and their pharmacological modulation. PI: prof. MVDr. J. Mojžiš, DrSc. |
|
EU founds: OPENMED CodeITMS2014+:313011V455. PI of activity 7.1: prof. MVDr. J. Mojžiš, DrSc. |
|
Organisational activities
|
|
Member of Scientific Board of Faculty of Medicine, Faculty of Natural Sciences and
University of PJ Šafarik - Pavol Jozef Šafárik University in Košice, 2011-2015
|
|
Member of the committee of the Slovak Pharmacological Society - Sloval Medical Society, 2010-until now
|
|
Member of juries for defendence of PhD. theses in pharmacology , Member of juries
for defendence of PhD. theses in Molecular Cytology - Pavol Jozef Šafárik University in Košice, 2004-until now
|
|
Deputy Chairman of the UPJŠ Attestation Commission in Košice - Pavol Jozef Šafárik University in Košice, 2015-until now
|
|
Member of commisions of Grant agencies (VEGA, APVV) - Ministry of Education, Science, Research and Sports, Slovak Republic, 2013-2021 (VEGA); 2015-until now (APVV)
|
|
Awards
|
|
- co-author of publications awarded as the best publications of Fac.Med. UPJS (1994, 1995) - 1st and co-author of publications awarded as the best publications of Fac.Med. UPJS (1996, 1998) - co-author (1997) of book (Pharmacology) awarded as the best monography of Fac. Med. UPJS - 1. author of lecture awarded as the best lecture in the frame of 49. Czech and Slovak Pharmacological congress in Bratislava (1999) - Honorary citizen of the City of Mobile, USA (1997) - award of Slovak Pharmacological Society for publishing activity - 1st author (2001) of book awarded as the best monography of Fac. Med. UPJS - co-author of publications awarded as the best publications of UPJS Faculty of Medicine (2002, 2003) - Co-author of publication awarded as the best publication of journal Psychiatry for prax (2012) - Rector´s Award for scientific research and publishing activity (2015)
|
|
Projects
|
|
In position of principal investigator. APVV. 1. Anticancer effect of natural compunds: focus to angiogenesis. APVV-0325-07; 2. Galectins and angiogenesis APVV-0408-12; 3. Cell interactions in the tumor microenvironment and their pharmacological modulations. APVV-16-0446; VEGA 1. Natural compounds and their use in chemoprevention/therapy on cancers. VEGA 1/1176/04 2. Effect of natural compounds and their synthetic derivatives on tumor angiogenesis. VEGA 1/4236/07 3. Anticancer effect of indole phytoalexins - focus to angiogenesis. 1/0302/10 4. Indole phytoalexins - mechanism of their anti-proliferative effect. VEGA 1/0322/14; 5. Effect of natural compunds on tumor microenvironment. VEGA 1/0753/17 6. Fibroblasts and tumor microenvironment: cell interactions and their pharmacological modulation. 1/0539/21 EU founds 1. Open scientific community for modern interdisciplinary research in medicine (OPENMED) – PI of activity 7.1
|
|
Other
|
|
- member of juries for defendence of PhD. theses in pharmacology and toxicology - expert for elaboration of accompaining material for registration of drug products - referee for evaluation of PhD. theses or publications for national or international scientific journals - member of Scientific Board Fac.Med. UPJS, Kosice (from 1997-2015) - member of Scientific Board UPJS, Kosice (from 2011-2015) - member of commisions of Grant agencies (VEGA, APVV) - member of editorial board Folia Cassoviensia - member of editorial board Internatiol Journal of Current Chemistry
|
