LF

RNDr. Jana Bzdiľová, PhD.   SK

Email:
 jana.janockova@upjs.sk
Homepage:
 https://www.upjs.sk/LF/zamestnanec/jana.janockova
Faculty:
LF UPJŠ - Pavol Jozef Šafárik University in Košice Faculty of Medicine
Department:
ZTB - Associated Tissue Bank
Office:
Phone:
 +421 55 234 3238
ORCID ID:
 https://orcid.org/0000-0002-2034-1860
RNDr. Jana Janockova, PhD. graduated at Faculty of Science, P. J. Safarik University in Košice, in the field of Biochemistry (PhD. 2015). After graduating, she worked as a researcher at the Biomedical Research Centre, University Hospital in Hradec Kralove (Czech Republic) in the laboratory of biochemistry and tissue cultures, where she was focused on in vitro analysis of biochemical and pharmacological activities of newly prepared substances as well as cell line production (tumor and non-tumor), which are then used in the cytotoxic evaluation of new series of drugs in order to reveal their toxic structural motifs. She was mainly involved in the development of new drug candidates for Alzheimer's disease, narcolepsy / insomnia, disinfectants and antidotes to organophosphate pesticide poisoning. She has been involved in leading and teaching undergraduate and postgraduate students as an Assistant Professor at the Department of Chemistry, University of Hradec Kralove. Scientific experience abroad: University of Coimbra, Portugal; Alma Mater Studiorum University of Bologna, Italy; University of Oviedo, Spain. Currently, she works as a researcher at the Associated Tissue Bank, Faculty of Medicine, UPJŠ in Kosice, where she specializes in the field of mesenchymal stem cells research and the production of extracellular vesicles and related mechanisms of bone and joint regeneration. In 2021, she obtained a scientific qualification IIa by the SAV commission. She participates in solving of projects APVV, VEGA, OPENMED. In the past, she participated in the solution of foreign projects 5x GAČR, 2x AZV and the international project Laser-Lab Europe. She is the author and co-author of 43 impacted publications (9 of them as the first author). Her works have been cited more than 594 times (WoS, April 2022, excluding self-citations) and her H-index is 14.
Higher education and further qualification growth
First degree of higher education:
Faculty of Science, P. J. Safarik University in Kosice, 2009, Chemistry
Second degree of higher education:
Department of Biochemistry, Faculty of Science, P. J. Safarik University in Kosice, 2011, Chemistry/Biochemistry
Third degree of higher education:
Department of Biochemistry, Faculty of Science, P. J. Safarik University in Kosice, 2015, Biochemistry

Research /art/ teacher profile

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Selected publications

ADC Janockova J., Slovinska L., Harvanova D., Spakova T. Rosocha J., New therapeutic approaches of mesenchymal stem cells-derived exosomes, Journal of Biomedical Science, 28 (2021). (2020: 8.410 - IF, Q1 – JCR, Q1 – SJR). Citácie: 10.

ADC Janockova J., Matejova J., Moravek M., Homolova L., Slovinska L., Nagyova A., Rak D., Sedlak M., Harvanova D., Spakova T. Rosocha J., Small extracellular vesicles derived from human chorionic MSCs as modern perspective towards cell-free therapy, Int J Mol Sci, 22 (2021). (2020: 5.924 - IF, Q1 – JCR, Q1 – SJR). Citácie: 0. 

ADC Janockova J., Korabecny J., Plsikova J., Babkova K., Konkolova E., Kucerova D., Vargova J., Koval J., Jendzelovsky R., Fedorocko P., Kasparkova J., Brabec V., Rosocha J., Soukup O., Hamulakova S., Kuca K., Kozurkova M., In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers, Journal of Enzyme Inhibition and Medicinal Chemistry, 34 (2019) 877-897. (2018: 4.027 – IF, Q1 – JCR, Q2 – SJR). Citácie: 5.

ADC Alfadly E.D., Elzahhar P.A., Tramarin A., Elkazaz S., Shaltout H., Abu-Serie M. M., Janockova J., Soukup O., Ghareeb D. A., El-Yazbi A. F., Rafeh R. W., Bakkar N-M. Z., Kobeissy F., Iriepa I., Moraleda I., Saudi M. N.S., Bartolini M., Belal A. S.F., Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase, Europ J Med Chem, 167 (2019) 161-186. (2018: 4.833 – IF, Q1 - JCR, Q1 – SJR). Citácie: 37.

ADC_Janockova J., Dolezal R., Nepovimova E., Kobrlova T., Benkova M., Kuca K., Konecny J., Mezeiova E., Melikova M., Hepnarova V., Ring A., Soukup O., Korabecny J., Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods, Molecules. 23 (2018). (2017: 3.098 – IF, Q2 – JCR, Q1 – SJR). Citácie: 2. 
Selected projects

U313011V455 - OPENMED

APVV – 17-0118: Mesenchymal stem cell exosomes as a potential alternative to the cell therapy in the treatment of osteoarthritis

VEGA – 1/0229/20: Analysis of the effect of exosomes produced by human mesenchymal stem cells on inflammatory chondrocytes in order to compare the effectiveness of the cell-free and cell therapy in the treatment of osteoarthritis

GAČR (2019-2021): Specific serotonin-dopamine modulators and their potential in a model of induced psychosis

GAČR 18-01734S (2018-2020): Butyrylcholinesterase reactivators for the preparation of pseudo-catalytic scavengers useful in organophosphorus intoxications

GAČR 17-13541S (2018-2020): Development of new radioprotective substances based on small molecular inhibitors

GAČR 17-08596S (2017-2019): New effective drugs in the treatment of narcolepsy

GAČR 16-13967S (2016-2019): Plasmonic nanoparticles for theranostics with tunable optothermal parameters

AZV 16-34390A (2016-2019): Development of new insecticides against environmentally friendly malaria-transmitting mosquitoes

AZV 15-30954A (2015-2018): Development of a multifunctional drug for Alzheimer's disease: a combination of an AChE inhibitor and a melatonin derivatives
International mobilities and visits
Faculty of Chemistry, Department of Physical and Analytical Chemistry, University of Oviedo, Spain, Oviedo, Spain, 09/2021 - 10/2021
Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Italy, Bologna, Italy, 10/2018 - 04/2019
Department of Chemistry, University of Coimbra, Portugal, Coimbra, Portugal, 04/2017
Department of Molecular Biophysics, Czech Academy of Science, Brno, Czech Republic, Brno, Czech Republic, 01/2015, 01/2014-04/2014
Department of Biochemical Science, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Czech Republic, Hradec Kralove, Czech Republic, 09/2010 - 02/2011
Centre of Advanced Studies, Faculty of Military Health Science in Hradec Kralove, University of Defence in Brno, Czech Republic, Hradec Kralove, Czech Republic, 12/2010 - 02/2011

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