doc. MUDr. Matej Škorvánek, PhD., univerzitný profesor

	Email:	matej.skorvanek@upjs.sk
	Homepage:	https://www.upjs.sk/LF/zamestnanec/matej.skorvanek
	Faculty:	LF UPJŠ - Pavol Jozef Šafárik University in Košice Faculty of Medicine
	Department:	NLK - Department of Neurology
	Office:	MH6O03E
	Phone:
	ORCID ID:	0000-0001-5497-8715

Assoc. Prof. Matej Škorvánek, MD, PhD. holds currently a position of Associated Professor and Head of Centre for rare movement disorders at Department of Neurology, LF UPJŠ and UNLP in Košice, Slovakia. He received his PhD title in 2014 at the University of Groningen, Netherlands, and became Associated Professor in 2018. During his specialization he attended study stays at universities in Prague, UCL in London, Groningen and Vienna. He has been a principal investigator or co-investigator of APVV, VEGA, COST, CEVA, IPDMS, IBM and ERDF grants. At present, he is a supervisor of 4 internal and 2 external PhD students with focus on movement disorders. He is the current chair of the Movement Disorders Section of the Slovak Neurological Society and a member of the Executive Committee of the Slovak Neurological Society, chair of the MDS European section educational committee, chair of the MDS Clinical Outcome Assessments Scientific Evaluation Committee, as well as other national and international working groups and committees (see section Others). He is the chair of 7 European congresses officially organized, supported or endorsed by the MDS. He has received domestic and foreign awards for his previous scientific work, including awards Personality of Science and Technology under 35 years for 2018 (awarded by the Ministry of Education of the Slovak Republic), the Guoth Prize for 2018 (awarded by the Slovak Medical Society for the extraordinary achievements of a physician under 38 years) as well as the prestigious MDS LEAP in 2015 (Leadership program for young movement disorder neurologists). He is currently coordinating several national and international multicentre projects focusing on non-motor, prodromal and genetic aspects of Parkinson's disease. These include the Quality of Life in Parkinson's Disease – QUALPD study, the Central European Group on Genetics of Movement Disorders - CEGEMOD and the PARCAS and PDBIOM studies to identify new biomarkers of prodromal Parkinson's disease (participation in other projects and collaborations below). His major clinical and research interest is also related to early diagnostics of rare hereditary hyperkinetic movement disorders, especially dystonia.

Higher education and further qualification growth

Second degree of higher education:

University of P. J. Šafárik in Košice, Medical Faculty, 2008, general medicine

Third degree of higher education:

University of P. J. Šafárik in Košice, Medical Faculty, 2014, 7.1.11 Neurology

Associate professor:

University of P. J. Šafárik in Košice, Medical Faculty, 2018, 7.1.11 Neurology

Research /art/ teacher profile

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Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
Study programme: State exam committee for pediatrics, study field: general medicine, II degree
Study programme: Committee for PhD study in 7.1.11 Neurology, study field: General medicine, III degree
Profile courses
Neurology I - general medicine, II degree
Neurodegenerative disorders - 7.1.11 Neurology, III degree
Vedecká práca - všeobecné lekárstvo, II degree
Scientific work - General medicine, II degree
Selected publications
ADC - Steel D, Zech M, Zhao C, Barwick KES, Burke D, Demailly D, Kumar KR, Zorzi G, Nardocci N, Kaiyrzhanov R, Wagner M, Iuso A, Berutti R, Škorvánek M, Necpál J, Davis R, Wiethoff S, Mankad K, Sudhakar S, Ferrini A, Sharma S, Kamsteeg EJ, Tijssen MA, Verschuuren C, van Egmond ME, Flowers JM, McEntagart M, Tucci A, Coubes P, Bustos BI, Gonzalez-Latapi P, Tisch S, Darveniza P, Gorman KM, Peall KJ, Bötzel K, Koch JC, Kmieć T, Plecko B, Boesch S, Haslinger B, Jech R, Garavaglia B, Wood N, Houlden H, Gissen P, Lubbe SJ, Sue CM, Cif L, Mencacci NE, Anderson G, Kurian MA, Winkelmann J; Genomics England Research Consortium. Loss-of-Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities. Ann Neurol. 2020 Nov;88(5):867-877. IF 9,037, Q1, cited 19x
ADC - Zech M, Jech R, Boesch S, Škorvánek M, Weber S, Wagner M, Zhao C, Jochim A, Necpál J, Dincer Y, Vill K, Distelmaier F, Stoklosa M, Krenn M, Grunwald S, Bock-Bierbaum T, Fečíková A, Havránková P, Roth J, Příhodová I, Adamovičová M, Ulmanová O, Bechyně K, Danhofer P, Veselý B, Haň V, Pavelekova P, Gdovinová Z, Mantel T, Meindl T, Sitzberger A, Schröder S, Blaschek A, Roser T, Bonfert MV, Haberlandt E, Plecko B, Leineweber B, Berweck S, Herberhold T, Langguth B, Švantnerová J, Minár M, Ramos-Rivera GA, Wojcik MH, Pajusalu S, Õunap K, Schatz UA, Pölsler L, Milenkovic I, Laccone F, Pilshofer V, Colombo R, Patzer S, Iuso A, Vera J, Troncoso M, Fang F, Prokisch H, Wilbert F, Eckenweiler M, Graf E, Westphal DS, Riedhammer KM, Brunet T, Alhaddad B, Berutti R, Strom TM, Hecht M, Baumann M, Wolf M, Telegrafi A, Person RE, Zamora FM, Henderson LB, Weise D, Musacchio T, Volkmann J, Szuto A, Becker J, Cremer K, Sycha T, Zimprich F, Kraus V, Makowski C, Gonzalez-Alegre P, Bardakjian TM, Ozelius LJ, Vetro A, Guerrini R, Maier E, Borggraefe I, Kuster A, Wortmann SB, Hackenberg A, Steinfeld R, Assmann B, Staufner C, Opladen T, Růžička E, Cohn RD, Dyment D, Chung WK, Engels H, Ceballos-Baumann A, Ploski R, Daumke O, Haslinger B, Mall V, Oexle K, Winkelmann J. Monogenic variants in dystonia: an exome-wide sequencing study. Lancet Neurol. 2020 Nov;19(11):908-918. IF 30,039, Q1, cited 18x
ADC - Skorvanek M, Gelpi E, Mechirova E, Ladomirjakova Z, Han V, Lesko N, Feketeova E, Repkova B, Urbancikova Z, Vargova A, Spisak P, Ribeiro Ventosa J, Kudela F, Kulcsarova K, Babinska S, Toth S, Gombosova L, Zakuciova M, Veseliny E, Trebuna F, Lutz MI, Gdovinova Z, Kovacs GG; PARCAS studygroup. α-Synuclein antibody 5G4 identifies manifest and prodromal Parkinson's disease in colonic mucosa. Mov Disord. 2018 Aug;33(8):1366-1368. IF 8,679, Q1, cited 4x
ADC - Skorvanek M, Goldman JG, Jahanshahi M, Marras C, Rektorova I, Schmand B, van Duijn E, Goetz CG, Weintraub D, Stebbins GT, Martinez-Martin P; members of the MDS Rating Scales Review Committee. Global scales for cognitive screening in Parkinson's disease: Critique and recommendations. Mov Disord. 2018 Feb;33(2):208-218. IF 8,679, Q1, cited 69x
ADC - Skorvanek M, Martinez-Martin P, Kovacs N, Zezula I, Rodriguez-Violante M, Corvol JC, Taba P, Seppi K, Levin O, Schrag A, Aviles-Olmos I, Alvarez-Sanchez M, Arakaki T, Aschermann Z, Benchetrit E, Benoit C, Bergareche-Yarza A, Cervantes-Arriaga A, Chade A, Cormier F, Datieva V, Gallagher DA, Garretto N, Gdovinova Z, Gershanik O, Grofik M, Han V, Kadastik-Eerme L, Kurtis MM, Mangone G, Martinez-Castrillo JC, Mendoza-Rodriguez A, Minar M, Moore HP, Muldmaa M, Mueller C, Pinter B, Poewe W, Rallmann K, Reiter E, Rodriguez-Blazquez C, Singer C, Valkovic P, Goetz CG, Stebbins GT. Relationship between the MDS-UPDRS and Quality of Life: A large multicenter study of 3206 patients. Parkinsonism Relat Disord. 2018 Jul;52:83-89. IF 3,926, Q1, cited 22x
Selected projects
APVV-18-0547: "New biomarkers of prodromal Parkinson’s disease" - principal investigator
VEGA 1/0596/19: "Identification and validation of new biomarkers of prodromal Parkinson’s disease in a large cohort of idiopathic REM sleep behavior disorder subjects" - principal investigator
ITMS2014+: 313011V455 supported by the Operational Programme Integrated Infrastructure, funded by the ERDF: Open scientific community for modern interdisciplinary research in medicine (OPENMED)“ - responsible investigator activity H6 Neurodegenerative disorders
ITMS2014+: 313022V631 supported by the Operational Programme Integrated Infrastructure, funded by the ERDF: "Early warning of Alzheimer disease and other neurodegeneraive disorders (EWA)" - professional guarantor
APVV-14-0415: "Novel biomarkers of premotor Parkinson’s disease" – deputy principal investigator
International mobilities and visits
Charles University in Prague, Czech republic, Kateřinská 30, Praha, january-february 2011, self-funded
University College London, Queens square, London, UK, march-april 2012, EAN department-department exchange programme
University of Groningen, Groningen, Holandsko, september 2012, Erasmus
University of Groningen, Groningen, Holandsko, september 2013, Erasmus
Medical University of Vienna, Vienna, Rakúsko, january 2017, APVV-14-0415
University of Groningen, Groningen, Netherlands, september 2016, APVV-14-0415
Organisational activities
Chair - Movement Disorders Section Slovak Neurological Society, 2018-2023
Chair - Working group for prevention of neurodegenerative disorders, Ministry of Health Slovak Republic, 2020-2022
Chair - Movement Disorder Society - Clinical Outcome Assessments Scientific Evaluation Committee, 2021-2023
Chair - Education committee, Movement Disorder Society - European section, 2021-2023
Member - Executive Committee Slovak Neurological Society, 2018-2023
Member - Scientific committee, Government Council for Mental Health of Slovak Republic
Member - Management committee – European Academy of Neurology Movement Disorders Scientific panel, 2022-2023
Member - European Academy of Neurology Teaching Course Subcommittee, 2022-2023
Member - Movement Disorders Society Leadership Steering Committee
Member - Movement Disorders Society Early and Prodromal PD Working Group of the Clinical Outcome Assessments (COA) Program, 2021-2023

Additional information

Awards

- „Personality of science and technology under 35 year“ for year 2018 (Awarded by the Ministry of Education, Science, Research and Sports of the Slovak Republic) - „Guoth award“ for year 2018 (awarded by the Slovak Medical Society for exceptional contributions of a physician under 38 years) - Best specialization thesis for year 2013 from the Slovak Neurological Society - Best scientific publication and scientific case reports for years 2013, 2015, 2017, 2018 and 2019 from the Slovak Neurological Society - MDS LEAP program: International LEAders Program for Young Movement Disorder Neurologists – 2015 MDS LEAP Awardee (mentor Khailash Bhatia) - Featured abstract presentation - 20th Annual International Parkinson and Movement Disorder Society Congress, Berlin, Germany - Best poster of the 30th Czech and Slovak Neurological Congress, Nov 2016, Prague, Czech republic

Projects

- APVV-0220-10: Longitudinal research of chronic invalidating disorders – Co-investigator - VEGA 1/0024/14 Colonic a-synuclein as a biomarker of premotor Parkinson’s disease – Deputy of principal investigator - APVV-14-0415 Novel biomarkers of premotor Parkinson’s disease – Deputy of principal investigator - VEGA 1/0724/15 Novel gene mutations in the etiopathogenesis of dystonia: their role, prevalence and manifestations – Co-investigator - COST BM1011 European network for the study of dystonia syndromes – Co-investigator - VEGA 1/0596/19 Identification and validation of new biomarkers of prodromal Parkinson’s disease in a large cohort of idiopathic REM sleep behavior disorder subjects - APVV-18-0547 New biomarkers of prodromal Parkinson’s disease - IBM Faculty Award – AI against Parkinson disease - Open scientific community for modern interdisciplinary research in medicine (OPENMED)“, ITMS2014+: 313011V455 supported by the Operational Programme Integrated Infrastructure, funded by the ERDF – Principal investigator for the working group on Neurodegenerative diseases - Early warning of Alzheimer disease and other neurodegeneraive disorders (EWA), ITMS2014+: 313022V631 supported by the Operational Programme Integrated Infrastructure, funded by the ERDF – principal investigator of the Parkinson’s disease module

International collaboration

- Central European Group on Genetics of Movement Disorders (CEGEMOD) - project coordinator (10 centers from V4 countries and the UK) - Quality of Life in Parkinson's Disease (QUALPD) projekt - project coordinator (25 centers from 15 countries in Europe and Americas) - Parkinson’s disease associated colonic alpha-synuclein study (PARCAS) - project coordinator - Prodromal Parkinson’s Disease Biomarker Study (PDBIOM) - project coordinator - Recommendations for use of rating scales for prodromal Parkinsons disease (Movement Disorder Society - MDS - commissioned) - project coordinator - Recommendations for use of rating scales for spasticity (MDS commissioned) - MDS COA SEC liaison (coordinator Prof. Robert Jech, Praha, Czech republic) - Recommendations for use of cognitive tests in Parkinsons disease (MDS commissioned) - MDS COA SEC liaison (coordinator Gert Guertsen, Amsterdam, Netherlands) - Implementation of DystonieNET project - Prof. Marina A.J. de Koning-Tijssen, Groningen, Netherlands - MJFF Global Genetics Parkinson's Disease - Prof. Christine Klein, Lubeck, Germany - Genetics of Dystonia (GenDy) - prof. Robert Jech, Praha, Czech republic, Assoc. Prof. Michael Zech, Munich, Germany - MultiDaT 2.0 project (evaluation of DaT scanos in patients with idiopathic RBD) - Prof. Dario Arnaldi, Genoa, Italy - Consortium for Global Diversity in Parkinsons Disease (CGD-PD) - scientific advisor (coordinator Prof. Jawad Bajwa, Riyadh, Saudi Arabia) - Idiopathic RBD Genetics Group - Prof. Ziv Gan-Or, Montreal, Kanada

Other

Current Membership in Societies, Task forces and Committees: • National - Executive Committee Member - Slovak Neurological Society - 5/2018 - Chair – Movement Disorders section of the Slovak Neurological Society - since 5/2018 - Chair – Working group on Neurodegenerative diseases, Ministry of Health of the Slovak Republic – since 3/2019 - Member – Council of the Government of the Slovak Republic for Mental Health – Scientific committee – since 6/2021 - Chair – Working group on Education, Council of the Government of the Slovak Republic for Mental Health – since 1/2022 - Member – Categorization committee of the Slovak Ministry of Health – working group on Neurology - Member – Academic Senate of the Medical Faculty of P. J. Safarik University in Kosice, Slovak Republic – since 3/2019 - Chair – Committee for science and research, Academic senate of the Medical Faculty, P. J. Safarik University, Kosice, Slovak Republic • International - Chair, MDS-ES European Education Committee – 2021-2023 - Ad-hoc member, MDS Education Committee – 2021-2023 - Chair, MDS Clinical Outcomes Assessment Scientific Evaluation Committee – since 2021 o Coordinator, Prodromal PD review subcommittee, since 2021 o Liaison, Spasticity subcommittee, since 2019 o Liaison, Cognitive tests in PD subcommittee, since 2021 - Member, MDS Leadership Steering Committee – since June 2017 - Member, MDS Early and Prodromal PD Working Group of the Clinical Outcome Assessments (COA) Program - Management Committee (MDS-ES representative), European Academy of Neurology (EAN), Movement Disorders scientific panel since 2021 - Member (MDS-ES representative), EAN Teaching Course Subcommittee – since 2021 Editorial board member - Parkinsonism and Related Disorders - Polish Neurology and Neurosurgery - Neurologia pre prax

Interesting links

https://www.researchgate.net/profile/Matej-Skorvanek https://scholar.google.sk/citations?user=bXFA1iIAAAAJ&hl=sk https://pubmed.ncbi.nlm.nih.gov/?term=skorvanek&sort=date

Further information

Taught courses and supervised study programmes