LF

RNDr. Michal Alexovič, PhD.   SK

Email:
 michal.alexovic@upjs.sk
Homepage:
 https://www.upjs.sk/LF/zamestnanec/michal.alexovic
Faculty:
LF UPJŠ - Pavol Jozef Šafárik University in Košice Faculty of Medicine
Department:
ULBF - Department of Medical and Clinical Biophysics
Office:
 MB4O21
Phone:
 +421 55 234 3514
ORCID ID:
 0000-0002-1618-1059
During his doctoral studies at the Department of Analytical Chemistry, Faculty of Science, UPJŠ in Košice, Slovakia (2010-2014), he focused on miniaturization and automation of sample pretreatment techniques for the spectrophotometric-based trace elemental analysis. With miniaturization of liquid phase microextraction and their automation using flow techniques, he has been dealing even several years after completing his third university degree. Since 2014, he has been working as an independent researcher at the Department of Medical & Clinical Biophysics, Faculty of Medicine, UPJŠ in Košice, Slovakia. His scientific interests include: (i.) Application of advanced biological sample pretreatment methods for the "shotgun" proteomic analysis followed by LC-MS/MS detection, (ii.) Use of modern ion trap-based mass spectrometry approaches for clinical proteomics, and (iii.) Bioinformatic evaluation of comparative proteome analysis of different cohorts. The currents topics of his clinical research are: (a.) Differential proteomic analysis of white blood cells isolated from peripheral blood of breast cancer patients, and (b.) State-of-the-art approaches for subtyping breast carcinomas at the protein biomarker analysis level. He is author/co-author of 34 original research papers/reviews. As of 10.07.2025, total WOS citations = 1100x, in 836 peer-reviewed publications, H-Index = 19. https://www.webofscience.com/wos/author/record/MVU-3433-2025
Higher education and further qualification growth
First degree of higher education:
Faculty of Science, University of P.J. Šafárik in Košice, Slovakia, 2005-2007, General Ecology and Ecology of Individual and Population
Second degree of higher education:
Faculty of Science, University of P.J. Šafárik in Košice, Slovakia, 2007-2010, General Ecology and Ecology of Individual and Population
Third degree of higher education:
Faculty of Science, University of P.J. Šafárik in Košice, Slovakia, 2010-2014, Analytical Chemistry

Research /art/ teacher profile

Display details  
Selected publications

ALEXOVIČ, Michal - HORSTKOTTE, Burkhard - SOLICH, Petr - SABO, Ján; Automation of static and dynamic non-dispersive liquid phase microextraction. Part 1: Approaches based on extractant drop-, plug-, film- and microflow formation; Analytica Chimica Acta 906 (2016) 22 - 40, IF: 5.95, Q1, 56x cited in SCOPUS database.

ALEXOVIČ, Michal - HORSTKOTTE, Burkhard - ŠRÁMKOVÁ, Ivana - SOLICH, Petr - SABO, Ján; Automation of dispersive liquid-liquid microextraction and related techniques. Approaches based on flow, batch, flow-batch and in-syringe modes; Trends In Analytical Chemistry 86 (2017) 39-55, IF: 7.03, Q1, 60x cited in SCOPUS database.

ALEXOVIČ, Michal - DOTSIKAS, Yannis - BOBER, Peter - SABO, Ján; Achievements in robotic automation of solvent extraction and related approaches for bioanalysis of pharmaceuticals; Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1092 (2018) 402-421, IF:2.81, Q2, 53x cited in SCOPUS database.

ALEXOVIČ, Michal - URBAN, Pawel L. - TABANI, Hadi - SABO, Ján; Recent advances in robotic protein sample preparation for clinical analysis and other biomedical applications; Clinica Chimica Acta: International Journal of Clinical Chemistry and Diagnostic Laboratory Medicine 507 (2020) 104-116, IF:3.87, Q1, 23x cited in SCOPUS database.

ALEXOVIČ, Michal - SABO, Ján - LONGUESPÉE, Rémi; Microproteomic sample preparation; Proteomics: Proteomics and Systems Biology 9 (2021) 2000318 1-16, IF: 3.98, Q1, 8x cited in SCOPUS database.
Selected projects

Integrative strategy in the development of personalized medicine of selected malignant tumors and its impact on quality of life , ITMS2014+: 313011V446, principal investigator: Assoc. Prof. Ján Sabo, PhD.

An innovative strategy for the diagnosis and treatment of breast cancer based on changes in the proteome of circulating leukocytes, 2020_APVV-19-0476, principal investigator: Assoc. Prof. Ján Sabo, PhD.
International mobilities and visits
University of Balearic Islands, Spain, Palma de Mallorca, 09/2011-11/2011, Prof. Dr. Víctor Cerdà, PhD.
Jagiellonian University, Poland, Krakow, 02/2013-06/2013, Prof. dr hab. Paweł Kościelniak
Charles University, Czech Republic, Hradec Králové, 03/2014, Prof. Dr. Petr Solich, PhD.

Additional information

Projects
1.) Project manager assistant, co-investigator: ITMS2014+: 313011V446 - Integrative strategy in the development of personalized medicine of selected malignant tumors and its impact on quality of life. 2.) Co-investigator: 2020_APVV-19-0476 - An innovative strategy for the diagnosis and treatment of breast cancer based on changes in the proteome of circulating leukocytes.
International collaboration
Collaborations in last 5 years: 1.) Prof. Paweł L. Urban - National Tsing Hua University, Hsinchu, Taiwan; 2.) Assoc. Prof. Hadi Tabani - Shahid Beheshti University, Tehran, Iran; 3.) Dr. Rémi Longuespée - Heidelberg University Hospital, Heidelberg, Germany; 4.) Prof. Katarina Davalieva - MASA, Skopje, North Macedonia.
Other
Associated research fields: Low-imput proteomics/microproteomics, Laboratory automation of protein analysis.
Interesting links
https://www.webofscience.com/wos/author/record/MVU-3433-2025
Hobbies
Film, Music, Nature, Politics

LF