RNDr. Tímea Špaková, PhD.

	Email:	timea.spakova@upjs.sk
	Homepage:	https://www.upjs.sk/LF/zamestnanec/timea.spakova
	Faculty:	LF UPJŠ - Pavol Jozef Šafárik University in Košice Faculty of Medicine
	Department:	ZTB - Associated Tissue Bank
	Office:	MA7O14
	Phone:	+421 55 234 3241
	ORCID ID:	https://orcid.org/0000-0001-6787-1925

RNDr. Timea Spakova, PhD. works as a researcher at the Associated Tissue Bank at the UPJŠ Faculty of Medicine in Košice (since 2009). She completed her university studies at Faculty of science UPJŠ in Košice in the field of chemistry, where after successfully defending her dissertation she obtained a PhD degree in the biochemistry study program in 2008. She is currently studying the mechanism of bone and connective tissue regeneration using autologous mesenchymal stem cells, platelet-rich plasma and their extracellular products. She is the author or co-author of more than 20 original scientific papers published in journals registered in CC databases, more than 18 scientific papers published in databases outside CC, 1 chapter in monographs. Her works have been cited more than 500 times in WoS or Scopus databases (H-index 11). She was/is the co-worker of several domestic projects APVV (3), VEGA (7) and NFP (4) and the chief worker of two VEGA projects.

Higher education and further qualification growth

Second degree of higher education:

Pavol Josef Safarik University in Kosice, Faculty of Science, 2004, Chemistry, Biochemistry

Third degree of higher education:

Pavol Josef Safarik University in Kosice, Faculty of Science, 2008, Chemistry, Biochemistry

Research /art/ teacher profile

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Selected publications
ADC Spakova T., Janockova J., Rosocha J., Characterization and therapeutic use of extracellular vesicles derived from platelets, International Journal of Molecular Sciences, 22 (2021) 9701. (2020: 5.924 - IF, Q1 - JCR, Q1 – SRJ). Citations: 1
ADC Janockova J., Matejova J., Moravek M., Homolova L., Slovinska L., Nagyova A., Rak D., Sedlak M., Harvanova D., Spakova T., Rosocha J., Small extracellular vesicles derived from human chorionic mscs as modern perspective towards cell-free therapy, International Journal of Molecular Sciences, 22 (2021). (2020: 5.924 – IF,Q1 – JCR, Q1 – SJR). Citations: 0
ADC Hunakova K., Hluchy M., Spakova T., Matejova J., Mudronova D., Kuricova M., Rosocha J., Ledecky V., Study of bilateral elbow joint osteoarthritis treatment using conditioned medium from allogeneic adipose tissue-derived MSCs in Labrador retrievers, Research in Veterinary Science, 132 (2020) 513-520. (2019: 1.892 – IF, Q1 – JCR, Q1 – SJR). Citations: 5
ADC Spakova T., Plsikova J., Harvanova D., Lacko M., Stolfa S., Rosocha J., Influence of kartogenin on chondrogenic differentiation of human bone Marrow-Derived MSCs in 2D culture and in Co-Cultivation with OA osteochondral explant, Molecules, 23 (2018) 1-16. (2017: 3.098 – IF, Q2 – JCR, Q1 – SJR). Citations: 16
ADM Spakova T., Amrichova J., Plsikova J., Harvanova D., Hornak S., Ledecky V., Rosocha J., A preliminary study comparing microfracture and local adherent transplantation of autologous adipose-derived stem cells followed by intraarticular injection of platelet-rich plasma for the treatment of chondral defects in rabbits, Cartilage, 9 (2018) 410-416. (2017: 2.621 - IF, Q1-JCR, Q1-SRJ). Citations: 5
Selected projects
313011V455 - Open scientific community for modern interdisciplinary research in medicine (OPENMED)
APVV – 17-0118: Exosomes derived from mesenchymal stem cells as potential alternatives to stem cell therapy for treatment of osteoarthritis
Vedúci projektu: VEGA – 1/0229/20: Examining the effect of human mesenchymal stem cells derived exosomes on inflammatory chondrocytes in order to compare the effectiveness of cell and cell-free therapy in OA treatment
Vedúci projektu: VEGA –1/0217/16: Study of the chondrogenic differentiation potential of mesenchymal stromal cells in vitro as a possible mechanism in cell therapy of osteoarthritis
APVV 0684/12: Study of immunomodulatory and regenerative properties of mesenchymal stromal cells on osteoarthritis model in vitro

Additional information

Awards

2006: the award for the best contribution at the seminar of young scientists dedicated to the memory of academician Boďa "New directions in veterinary physiology" 2008: the award of the Dean of the Faculty of Science of UPJŠ for the scientific-research activity of PhD students 2015: the award for the presentation in the section "Cell Metabolism, Physiology, Molecular Biology and Genetics" at the Interactive Conference of Young Scientists (Preveda) 2019: the Literary Fund Award in the Section for Scientific and Professional Literature and Computer Programs in the category of natural and medical sciences for a significant scientific response to the work: Tímea Špaková et al. Treatment of knee joint osteoarthritis with autologous platelet-rich plasma in comparison with hyaluronic acid. American Journal of Physical Medicine & Rehabilitation, ISSN 0894-9115, Vol. 91, no. 5 (2012), p. 411-417.