PF

RNDr. Ján Košuth, PhD.   SK

Email:
jan.kosuth@upjs.sk
Homepage:
www.upjs.sk/PF/zamestnanec/jan.kosuth/
Faculty:
PF UPJŠ - Pavol Jozef Šafárik University in Košice, Faculty of Science
Department:
ÚBEV - Institute of Biology and Ecology
Office:
RB1O117
Phone:
+421 55 234 1205
ORCID ID:
0000-0001-5584-8728

Higher education and further qualification growth
Second degree of higher education:
P.J. Šafárik University in Košice, 2000, Biology
Third degree of higher education:
P.J.Šafárik University in Košice, 2008, Genetics

Research /art/ teacher profile

Display details  
Selected publications
Tonelli Gombalová, Z., Košuth, J., Alexovič Matiašová, A., ...Daxnerová, Z., Ševc, J. Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. Journal of Comparative Neurology, 2020, 528(15), pp. 2523–2550
Košuth, J., Farkašovská, M., Mochnacký, F., Daxnerová, Z., Ševc, J. Selection of reliable reference genes for analysis of gene expression in spinal cord during rat postnatal development and after injury. Brain Sciences, 2020, 10(1), 6
Vranová, E., Kopcsayová, D., Košuth, J., Colinas, M. Mutant-Based Model of Two Independent Pathways for Carotenoid-Mediated Chloroplast Biogenesis in Arabidopsis Embryos. Frontiers in Plant Science, 2019, 10, 1034
Majerník, M., Jendželovský, R., Babinčák, M., ...Buríková, M., Fedoročko, P. Novel insights into the effect of hyperforin and photodynamic therapy with hypericin on chosen angiogenic factors in colorectal micro-tumors created on chorioallantoic membrane. International Journal of Molecular Sciences, 2019, 20(12), 3004
Babinčák, M., Jendželovský, R., Košuth, J., ...Zdráhal, Z., Fedoročko, P. Death receptor 5 (Tnfrsf10b) is upregulated and trail resistance is reversed in hypoxia and normoxia in colorectal cancer cell lines after treatment with skyrin, the active metabolite of hypericum spp. Cancers, 2021, 13(7), 1646
Selected projects

VEGA 1/0926/17 The role of GGPPS in isoprenoid biosynthetic pathway.

APVV-15-0239. Analýza potenciálu a úlohy výstelky centrálneho kanála pri regenerácii miechy.
VEGA 1/0635/16, Cerebrospinálny mok kontaktujúce neuróny (CSF-cNs) a ich úloha v mieche cicavcov.
VEGA 1/0760/20, Detekcia apoptotických procesov v bunkách nervového systému pomocou imunofluorescenčných metód aplikovaných v in vitro a in vivo modeloch
VEGA 1/0869/21, Špecifickou RNA podmienená aktivácia nanočastíc z nukleových kyselín
International mobilities and visits
University Oulu, Department of Botany, University of Oulu, Finland, 03/2002-05/2002, Erasmus
ETHZ, Group of Plant Biotechnology, ETH Zuerich, Switzerland, 02/2013-01/2014, SCIEX

Additional information

Projects
VVGS UPJŠ 53./2006 Characterization of selected Hypericum taxa – biosynthesis of naphtodianthrones, micropropagation and long-term storage
VVGS 52./2006 Biosynthesis of taxanes in in vitro cultures of Taxus baccata L., quantification of taxanes and expression of key enzymes in involved in the biosynthesis
VEGA 1/2326/05 Study of expression of Hyp-1 gene, coding for the key enzyme in hypericin biosynthesis. (2005-2007)
VEGA 1/1273/04 The study dbat gene expression in cell cultures of Taxus baccata L. (2004-2006)
APVT-20-003704 Hypericum perforatum L.: The Genetic aspects of hypericin biosynthesis and hypericin cytotoxic effects. (2005-2007)
Hobbies
Sleeping
Eating

Further information


PF