Email:
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jan.kosuth@upjs.sk | |
Homepage:
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www.upjs.sk/PF/zamestnanec/jan.kosuth/ | |
Faculty:
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PF UPJŠ
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Pavol Jozef Šafárik University in Košice, Faculty of Science
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Department:
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ÚBEV
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Institute of Biology and Ecology
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Office:
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RB1O117 | |
Phone:
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+421 55 234 1205 | |
ORCID ID:
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0000-0001-5584-8728 |
Selected publications
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Tonelli Gombalová, Z., Košuth, J., Alexovič Matiašová, A., ...Daxnerová, Z., Ševc, J. Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. Journal of Comparative Neurology, 2020, 528(15), pp. 2523–2550
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Košuth, J., Farkašovská, M., Mochnacký, F., Daxnerová, Z., Ševc, J. Selection of reliable reference genes for analysis of gene expression in spinal cord during rat postnatal development and after injury. Brain Sciences, 2020, 10(1), 6
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Vranová, E., Kopcsayová, D., Košuth, J., Colinas, M. Mutant-Based Model of Two Independent Pathways for Carotenoid-Mediated Chloroplast Biogenesis in Arabidopsis Embryos. Frontiers in Plant Science, 2019, 10, 1034
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Majerník, M., Jendželovský, R., Babinčák, M., ...Buríková, M., Fedoročko, P. Novel insights into the effect of hyperforin and photodynamic therapy with hypericin on chosen angiogenic factors in colorectal micro-tumors created on chorioallantoic membrane. International Journal of Molecular Sciences, 2019, 20(12), 3004
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Babinčák, M., Jendželovský, R., Košuth, J., ...Zdráhal, Z., Fedoročko, P. Death receptor 5 (Tnfrsf10b) is upregulated and trail resistance is reversed in hypoxia and normoxia in colorectal cancer cell lines after treatment with skyrin, the active metabolite of hypericum spp. Cancers, 2021, 13(7), 1646
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Selected projects
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VEGA 1/0926/17 The role of GGPPS in isoprenoid biosynthetic pathway. |
APVV-15-0239. Analýza potenciálu a úlohy výstelky centrálneho kanála pri regenerácii miechy.
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VEGA 1/0635/16, Cerebrospinálny mok kontaktujúce neuróny (CSF-cNs) a ich úloha v mieche cicavcov.
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VEGA 1/0760/20, Detekcia apoptotických procesov v bunkách nervového systému pomocou imunofluorescenčných metód aplikovaných v in vitro a in vivo modeloch
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VEGA 1/0869/21, Špecifickou RNA podmienená aktivácia nanočastíc z nukleových kyselín
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International mobilities and visits
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University Oulu, Department of Botany, University of Oulu, Finland, 03/2002-05/2002, Erasmus
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ETHZ, Group of Plant Biotechnology, ETH Zuerich, Switzerland, 02/2013-01/2014, SCIEX
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Projects
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VVGS UPJŠ 53./2006 Characterization of selected Hypericum taxa – biosynthesis of naphtodianthrones, micropropagation and long-term storage
VVGS 52./2006 Biosynthesis of taxanes in in vitro cultures of Taxus baccata L., quantification of taxanes and expression of key enzymes in involved in the biosynthesis VEGA 1/2326/05 Study of expression of Hyp-1 gene, coding for the key enzyme in hypericin biosynthesis. (2005-2007) VEGA 1/1273/04 The study dbat gene expression in cell cultures of Taxus baccata L. (2004-2006) APVT-20-003704 Hypericum perforatum L.: The Genetic aspects of hypericin biosynthesis and hypericin cytotoxic effects. (2005-2007) |
Hobbies
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Sleeping
Eating |