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Email:
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ladislav.janovec@upjs.sk | |
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Homepage:
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https://www.upjs.sk/PF/zamestnanec/ladislav.janovec | |
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Faculty:
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PF UPJŠ
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Pavol Jozef Šafárik University in Košice, Faculty of Science
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Department:
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ÚCHV
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Institute of Chemistry
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Office:
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RB2L10 | |
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Phone:
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+421 55 234 1197, 2395 | |
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ORCID ID:
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https://orcid.org/0000-0001-5769-2632 |
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Overview of the responsibility for
the delivery, development and quality assurance of the study programme or its part
at the university in the current academic year
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Study programme: OCHd - organic chemistry - (single degree study, doctoral level degree, full time form), study field: 17.- Organic chemistry, III. degree
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Study programme: OCHm - organic chemistry - (single degree study, master level degree, full time form), study field: 17.- Organic chemistry, II: degree
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Profile courses
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ÚCHV/PAKM/04 - Practical application of quantum chemical methods in organic chemistry - OCHd - organic chemistry - (single degree study, doctoral level degree, full time
form), III degree
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ÚCHV/BOC/03 - Bioorganic chemistry - OCHm - organic chemistry - (single degree study, master level degree, full time form), II degree
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ÚCHV/MSM1/00 - Modern synthetic methods - OCHm - organic chemistry - (single degree study, master level degree, full time form), II degree
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Selected publications
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ADC - Nunhart, P., Konkoľová, E., Janovec, L., Jendželovský, R., Vargová, J., Ševc, J., Matejová, M., Miltáková, B., Fedoročko, P., Kozurkova, M. Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity (2020) Bioorg. Chem., 94, art. no. 103393. IF 4.831; Q1 (Chemistry, Organic); Citations 6 |
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ADC - Janovec, L., Janočková, J., Matejová, M., Konkoľová, E., Paulíková, H., Lichancová, D., Júnošová, L., Hamuľaková, S., Imrich, J., Kožurková, M. Proliferation inhibition of novel diphenylamine derivatives (2019) Bioorg. Chem., 83, pp. 487-499. IF 4.831; Q1 (Chemistry, Organic);Citations 6 |
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V3 - Krochtová K., Halečková A., Janovec L., Blizniaková M., Kušnírová K., Kožurková M. Novel 3,9-Disubstituted Acridines with Strong Inhibition Activity against Topoisomerase I: Synthesis, Biological Evaluation and Molecular Docking Study (2023) Molecules, 28 (3), art. no. 1308; IF 4.600; Q2 (Chemistry, Multidisciplinary); Citations 0 |
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ADC - Janovec, L., Kovacova, E., Semelakova, M., Kvakova, M., Kupka, D., Jager, D., Kozurkova, M. Synthesis of novel biologically active proflavine ureas designed on the basis of predicted entropy changes (2021) Molecules, 26 (16), art. no. 4860, . IF 4.411; Q2 (Chemistry, Multidisciplinary); Citations 0 |
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ADM - Hamulakova, S., Janovec, L., Soukup, O., Jun, D., Janockova, J., Hrabinova, M., Sepsova, V., Kuca, K. Tacrine-coumarin and tacrine-7-chloroquinoline hybrids with thiourea linkers: Cholinesterase inhibition properties, kinetic study, molecular docking and permeability assay for blood-brain barrier (2018) Curr. Alzheimer Res., 15 (12), pp. 1096-1105. IF 3.271; Q2 (Clinical Neurology); Citations 5 |
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Selected projects
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VEGA 1/0016/18 : " Study of cytotoxic activity of new coumarin derivatives modified by acridine, tacrine and anthracene skeleton " Principal Investigator - prof. RNDr. Mária Kožurková, Csc., Position on the project: representative of the project Duration: 2018 - 2021 |
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APVV-18-0285: " Understanding the mechanism of IgG inactivation using individual Hsp70 shaperone molecules and laser optical tweezers " Principal Investigator - RNDr. Gabriel Žoldak, PhD. Position on the project: co-investigator of the project Duration: 2019 - 2023 |
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VEGA 1/0037/22 : "Development and research of new pharmacophores based on acridine and coumarin with antimicrobial and antitumor effects " Principal Investigator - prof. RNDr. Mária Kožurková, Csc., Position on the project: representative of the project Duration: 2022 - 2025 |
