 |
Email:
|
peter.fedorocko@upjs.sk |
|
Homepage:
|
https://www.upjs.sk/PF/zamestnanec/peter.fedorocko | |
|
Faculty:
|
PF UPJŠ
-
Pavol Jozef Šafárik University in Košice, Faculty of Science
|
|
|
Department:
|
ÚBEV
-
Institute of Biology and Ecology
|
|
|
Office:
|
RB1O105 | |
|
Phone:
|
+421 55 234 1182 | |
|
ORCID ID:
|
http://orcid.org/0000-0002-1138-6282 |
|
Overview of the responsibility for
the delivery, development and quality assurance of the study programme or its part
at the university in the current academic year
|
|
Study programme: Molecular Biology, study field: Biology, Third degree degree
|
|
Study programme: Genetics and Molecular Cytology, study field: Biology, Second degree degree
|
|
Profile courses
|
|
ÚBEV/BKB/20 - Biology of Stem Cell - Genetics and Molecular Biology, Second degree
|
|
ÚBEV/CTP1/01 - Cytopathology - Genetics and Molecular Biology, Second degree and third degree
|
|
ÚBEV/ETB1/99 - Experimental Technics in Bology - Biology, First degree
|
|
Overview of the responsibility for
the development and quality of the field of habilitation procedure and inaugural procedure
in the current academic year
|
|
Name of the field of habilitation procedure and inaugural procedure:
Biology, study field to which it is assigned: Biology
|
|
Selected publications
|
|
GYURÁSZOVÁ, Katarína - MIKEŠ, Jaromír - HALABURKOVÁ, Andrea - JENDŽELOVSKÝ, Rastislav - FEDOROČKO, Peter. YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy. In: Photochemical & Photobiological Sciences. - ISSN 1474-905X. - Vol. 15, no. 6 (2016), s. 812-821. - DOI: 10.1039/c5pp00438a |
|
HALABURKOVÁ, Andrea - JENDŽELOVSKÝ, Rastislav - KOVAĽ, Ján - HERCEG, Zdenko - FEDOROČKO, Peter - GHANTOUS, Akram. Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A. In: Clinical Epigenetics. - ISSN 1868-7083. - Vol. 9 (2017), art.no. 62. - DOI 10.1186/s13148-017-0359-x |
|
VARGOVÁ, Jana - MIKEŠ, Jaromír - JENDŽELOVSKÝ, Rastislav - MIKEŠOVÁ, Lucia - KUCHÁROVÁ, Barbora - ČULKA, Ľubomír - FEDR, Radek - REMŠÍK, Ján - SOUČEK, Karel - KOZUBÍK, Alois - FEDOROČKO, Peter. Hypericin affects cancer side populations via competitive inhibition of BCRP. In: Biomedicine & Pharmacotherapy. - ISSN 0753-3322. - č. 99 (2018), s. 511-522. - DOI 10.1016/j.biopha.2018.01.074 |
|
MAJERNÍK, Martin - JENDŽELOVSKÝ, Rastislav - BABINČÁK, Marián - KOŠUTH, Ján - ŠEVC, Juraj - TONELLI GOMBALOVÁ, Zuzana - JENDŽELOVSKÁ, Zuzana - BURÍKOVÁ, Monika - FEDOROČKO, Peter. Novel Insights into the Effect of Hyperforin and Photodynamic Therapy with Hypericin on Chosen Angiogenic Factors in Colorectal Micro-Tumors Created on Chorioallantoic Membrane. In: International Journal of Molecular Sciences: Open Access Journal. - ISSN 1661-6596. - Roč. 20, č. 12 (2019), art. no. 3004, s. [1-24]. - DOI 10.3390/ijms20123004 |
|
BABINČÁK, Marián - JENDŽELOVSKÝ, Rastislav - KOŠUTH, Ján - MAJERNÍK, Martin - VARGOVÁ, Jana - MIKULÁŠEK, Kamil - ZDRÁHAL, Zbyněk - FEDOROČKO, Peter. Death receptor 5 (Tnfrsf10b) is upregulated and trail resistance is reversed in hypoxia and normoxia in colorectal cancer cell lines after treatment with skyrin, the active metabolite of hypericum spp. In: Cancers. - ISSN 2072-6694. - Roč. 13, č. 7 (2021), art.no. 1646., s. [1-30]. - DOI 10.3390/cancers13071646 |
|
Selected projects
|
|
Scientific Grant Agency of the Ministry of Education, Science, Research and Sport of the Slovak Republic and the Slovak Academy of Sciences: 1/0022/19: Hypoxia and Polymorphism of BCRP Transporter as the Factors Affecting Hypericin Accumulation and Efficiency in vitro and ex ovo. 1.1.2019 – 31.12. 2022 Principal investigator |
|
Scientific Grant Agency of the Ministry of Education, Science, Research and Sport of the Slovak Republic and the Slovak Academy of Sciences: 1/0147/15: Pleiotropic Effect of Non-Activated and Photo-Activated Hypericin on the Factors Affecting Multidrug Resistance in Cancer Cells. 1.1.2015 – 31.12.2018 Principal investigator |
|
Slovak Research and Development Agency: APVV-18-0125: Novel Anthraquinones from Natural Sources for Biomedical Applications. 1.7.2019 – 30.6.2023 Member of the research team |
|
Slovak Research and Development Agency: APVV-14-0154: Transcriptome, Metabolome and Signalome of Bioactive Compounds with Anticancer Effects in the Genus Hypericum. 1.7.2015 – 30.6.2019 Member of the research team |
|
Integrated Infrastructure Operational Program Project: Open Scientific Community for Modern Interdisciplinary Medical Research (OPENMED), ITMS code 2014+ 313011V455. 11/2019 – 12/2023 Guarantor research activity |
|
Organisational activities
|
|
Member - Scientific Board of Faculty of Science and Scientific Board of Pavol Jozef Šafárik
University in Košice, 2000 - up to now (SB FS), 2008 - up to now (SB PJSU in Košice)
|
|
Member - Scientific Board of Biomedical Research Center Slovak Academy of Sciences, 2020 - up to now
|
|
Member - Council for Natural Sciences, Slovak Research and Development Agency, 2014 - up to now
|
|
Member and/or chairman - Scientific Grant Agency of the Ministry of Education, Science, Research and Sport
of the Slovak Republic and the Slovak Academy of Sciences (for Biological Sciences), 2002-2008 (in perion 2005-2008 chairman) and 2012-2021
|
|
Member - Board of Trustees of the Cancer Research Foundation, 2013 - up to now
|
|
Awards
|
|
■ Award of Society for Radiotherapy, Radiology and Radiation Physics of the Slovak Medicine Society for best paper in 1992; ■ Faculty of Science Dean's Award for Research and Creative Achievements, 1999, 2003 and 2009; ■ Silver Medal of the Faculty of Science, Pavol Jozef Šafárik University in Košice on the occasion of the 45th anniversary of Faculty of Science; ■ Gold Medal of the Faculty of Science, Pavol Jozef Šafárik University in Košice on the occasion of the 50th anniversary of Faculty of Science; ■ Pavol Jozef Šafárik University in Košice Rector's Award for Research and Creative Achievements (2012).
|
|
Projects
|
|
■ Scientific Grant Agency of the Ministry of Education, Science, Research and Sport of the Slovak Republic and the Slovak Academy of Sciences: 1/0022/19: Hypoxia and Polymorphism of BCRP Transporter as the Factors Affecting Hypericin Accumulation and Efficiency in vitro and ex ovo. Principal investigator; ■ Scientific Grant Agency of the Ministry of Education, Science, Research and Sport of the Slovak Republic and the Slovak Academy of Sciences: 1/0147/15: Pleiotropic Effect of Non-Activated and Photo-Activated Hypericin on the Factors Affecting Multidrug Resistance in Cancer Cells. Principal investigator; ■ Slovak Research and Development Agency: APVV-18-0125: Novel Anthraquinones from Natural Sources for Biomedical Applications. Member of the research team; ■ Slovak Research and Development Agency: APVV-14-0154: Transcriptome, Metabolome and Signalome of Bioactive Compounds with Anticancer Effects in the Genus Hypericum. Member of the research team; ■ Integrated Infrastructure Operational Program Project: Open Scientific Community for Modern Interdisciplinary Medical Research (OPENMED), ITMS code 2014+ 313011V455, Guarantor research activity; ■ Network of excellent workplaces for oncology (SEPO), ITMS code 26220120024, Professional project guarantor ■ Creating infrastructure in centre of excellence SEPO-II, ITMS code 26220120039, Professional project guarantor ■ Innovation of the technological process of preparation of the immunomodulatory preparation Transfer factor, verification of its effectiveness, safety and composition, ITMS code 26220220157, Professional project guarantor ■ Medical University Science Park in Košice (MediPark, Košice), ITMS code 26220220185, Professional project guarantor
|
|
International collaboration
|
|
■ Institute of Biophysics, Academy of Science of the Czech Republic, Brno; ■ University of Naples Federico II, Department of Biologia e Patologia Cellulare e Molecolare, Naples, Italy; ■ Louis Pasteur Hospital, Košice; ■ Tissue Bank of Burns Centre and Plastic Surgery, The First Private Hospital Ltd., Košice-Šaca; ■ Gyncare, Ltd., Košice.
|
|
Other
|
|
■ Chairman of Departmental Committees for Doctoral Studies in Molecular Cytology; ■ Member of Departmental Committees for Doctoral Studies in Genetics and Animal Physiology at Pavol Jozef Šafárik University in Košice, Faculty of Science; ■ Member of Departmental Committees for Doctoral Studies in Pharmacy at Pavol Jozef Šafárik University in Košice, Faculty of Medicine; ■ Member of Departmental Committees for Doctoral Studies in Immunology at University of Veterinary Medicine and Pharmacy in Košice; ■ Member of Departmental Committees for Doctoral Studies in Genetics at Comenius University Bratislava; ■ Member of Departmental Committees for Doctoral Studies in Biochemistry at Slovak University of Technology in Bratislava, Faculty of Chemical and Food Technology, Bratislava;
|
